Probiotic-derived ecto-5’-nucleotidase produces anti-inflammatory adenosine metabolites in Treg-deficient scurfy mice

Probiotic Limosilactobacillus reuteri DSM 17938 (DSM 17938) prolonges the survival of Treg-deficient scurfy (SF) mice and reduces multiorgan inflammation by a process requiring adenosine receptor 2A (A(2A)) on T cells. We hypothesized that L. reuteri-derived ecto-5’-nucleotidase (ecto-5’NT) activity...

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Detalles Bibliográficos
Autores principales: Liu, Yuying, Armbrister, Shabba A., Okeugo, Beanna, Mills, Tingting W., Daniel, Rhea C., Oh, Jee-Hwan, Pijkeren, Jan-Peter, Park, Evelyn S., Saleh, Zeina M., Lahiri, Sharmistha, Roos, Stefan, Rhoads, J Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104250/
https://www.ncbi.nlm.nih.gov/pubmed/37066419
http://dx.doi.org/10.21203/rs.3.rs-2781715/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104250/
https://www.ncbi.nlm.nih.gov/pubmed/37066419
http://dx.doi.org/10.21203/rs.3.rs-2781715/v1

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