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Pregnancy programs epigenetic and transcriptional exhaustion in memory CD8(+) T cells
Alloreactive memory T cells, unlike naive T cells, fail to be restrained by transplantation tolerance protocols or regulatory T cells, and therefore represent a critical barrier to long-term graft acceptance. Using female mice sensitized by rejection of fully-mismatched paternal skin allografts, we...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Journal Experts
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104270/ https://www.ncbi.nlm.nih.gov/pubmed/37066154 http://dx.doi.org/10.21203/rs.3.rs-2196637/v1 |