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SOX2 downregulation of PML increases HCMV gene expression and growth of glioma cells

The presence of human cytomegalovirus (HCMV) in glioblastoma (GBM) and improved outcomes of GBM patients receiving therapies targeting the virus have implicated HCMV in GBM progression. However, a unifying mechanism that accounts for the contribution of HCMV to the malignant phenotype of GBM remains...

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Detalles Bibliográficos
Autores principales: Wen, Le, Wang, Xian-Zhang, Qiu, Yong, Zhou, Yue-Peng, Zhang, Qing-Yang, Cheng, Shuang, Sun, Jin-Yan, Jiang, Xing-Jun, Rayner, Simon, Britt, William J., Chen, Jian, Hu, Fei, Li, Fang-Cheng, Luo, Min-Hua, Cheng, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104302/
https://www.ncbi.nlm.nih.gov/pubmed/37058447
http://dx.doi.org/10.1371/journal.ppat.1011316