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SOX2 downregulation of PML increases HCMV gene expression and growth of glioma cells
The presence of human cytomegalovirus (HCMV) in glioblastoma (GBM) and improved outcomes of GBM patients receiving therapies targeting the virus have implicated HCMV in GBM progression. However, a unifying mechanism that accounts for the contribution of HCMV to the malignant phenotype of GBM remains...
Autores principales: | Wen, Le, Wang, Xian-Zhang, Qiu, Yong, Zhou, Yue-Peng, Zhang, Qing-Yang, Cheng, Shuang, Sun, Jin-Yan, Jiang, Xing-Jun, Rayner, Simon, Britt, William J., Chen, Jian, Hu, Fei, Li, Fang-Cheng, Luo, Min-Hua, Cheng, Han |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104302/ https://www.ncbi.nlm.nih.gov/pubmed/37058447 http://dx.doi.org/10.1371/journal.ppat.1011316 |
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