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GSK-3β inhibition alleviates arthritis pain via reducing spinal mitochondrial reactive oxygen species level and inflammation

Pain is the main symptom of osteoarthritis, which severely reduces the patients’ quality of life. Stimulated neuroinflammation and elevated mitochondrial oxidative stress are associated arthritis pain. In the present study, arthritis model was established by intra-articular injection of complete Fre...

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Detalles Bibliográficos
Autores principales: Yang, He-Yu, Sun, Xu, Zhen, Shu-Qing, Yu, Liang-Zhu, Ding, Jie-Qiong, Liu, Ling, Xie, Min, Zhu, Hai-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104309/
https://www.ncbi.nlm.nih.gov/pubmed/37058473
http://dx.doi.org/10.1371/journal.pone.0284332

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