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GSK-3β inhibition alleviates arthritis pain via reducing spinal mitochondrial reactive oxygen species level and inflammation
Pain is the main symptom of osteoarthritis, which severely reduces the patients’ quality of life. Stimulated neuroinflammation and elevated mitochondrial oxidative stress are associated arthritis pain. In the present study, arthritis model was established by intra-articular injection of complete Fre...
Autores principales: | Yang, He-Yu, Sun, Xu, Zhen, Shu-Qing, Yu, Liang-Zhu, Ding, Jie-Qiong, Liu, Ling, Xie, Min, Zhu, Hai-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104309/ https://www.ncbi.nlm.nih.gov/pubmed/37058473 http://dx.doi.org/10.1371/journal.pone.0284332 |
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