Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies

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Plus-strand RNA viruses are the largest group of viruses. Many are human pathogens that inflict a socio-economic burden. Interestingly, plus-strand RNA viruses share remarkable similarities in their replication. A hallmark of plus-strand RNA viruses is the remodeling of intracellular membranes to es...

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Detalles Bibliográficos
Autores principales: Zitzmann, Carolin, Dächert, Christopher, Schmid, Bianca, van der Schaar, Hilde, van Hemert, Martijn, Perelson, Alan S., van Kuppeveld, Frank J. M., Bartenschlager, Ralf, Binder, Marco, Kaderali, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104377/
https://www.ncbi.nlm.nih.gov/pubmed/37014904
http://dx.doi.org/10.1371/journal.pcbi.1010423
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