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Nutraceutical and Health-Promoting Potential of Lactoferrin, an Iron-Binding Protein in Human and Animal: Current Knowledge

Lactoferrin is a natural cationic iron-binding glycoprotein of the transferrin family found in bovine milk and other exocrine secretions, including lacrimal fluid, saliva, and bile. Lactoferrin has been investigated for its numerous powerful influences, including anticancer, anti-inflammatory, anti-...

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Autores principales: Ashraf, Muhammad Faizan, Zubair, Dawood, Bashir, Muhammad Noaman, Alagawany, Mahmoud, Ahmed, Shabbir, Shah, Qurban Ali, Buzdar, Jameel Ahmed, Arain, Muhammad Asif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104436/
https://www.ncbi.nlm.nih.gov/pubmed/37059920
http://dx.doi.org/10.1007/s12011-023-03658-4
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author Ashraf, Muhammad Faizan
Zubair, Dawood
Bashir, Muhammad Noaman
Alagawany, Mahmoud
Ahmed, Shabbir
Shah, Qurban Ali
Buzdar, Jameel Ahmed
Arain, Muhammad Asif
author_facet Ashraf, Muhammad Faizan
Zubair, Dawood
Bashir, Muhammad Noaman
Alagawany, Mahmoud
Ahmed, Shabbir
Shah, Qurban Ali
Buzdar, Jameel Ahmed
Arain, Muhammad Asif
author_sort Ashraf, Muhammad Faizan
collection PubMed
description Lactoferrin is a natural cationic iron-binding glycoprotein of the transferrin family found in bovine milk and other exocrine secretions, including lacrimal fluid, saliva, and bile. Lactoferrin has been investigated for its numerous powerful influences, including anticancer, anti-inflammatory, anti-oxidant, anti-osteoporotic, antifungal, antibacterial, antiviral, immunomodulatory, hepatoprotective, and other beneficial health effects. Lactoferrin demonstrated several nutraceutical and pharmaceutical potentials and have a significant impact on improving the health of humans and animals. Lactoferrin plays a critical role in keeping the normal physiological homeostasis associated with the development of pathological disorders. The current review highlights the medicinal value, nutraceutical role, therapeutic application, and outstanding favorable health sides of lactoferrin, which would benefit from more exploration of this glycoprotein for the design of effective medicines, drugs, and pharmaceuticals for safeguarding different health issues in animals and humans.
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spelling pubmed-101044362023-04-17 Nutraceutical and Health-Promoting Potential of Lactoferrin, an Iron-Binding Protein in Human and Animal: Current Knowledge Ashraf, Muhammad Faizan Zubair, Dawood Bashir, Muhammad Noaman Alagawany, Mahmoud Ahmed, Shabbir Shah, Qurban Ali Buzdar, Jameel Ahmed Arain, Muhammad Asif Biol Trace Elem Res Article Lactoferrin is a natural cationic iron-binding glycoprotein of the transferrin family found in bovine milk and other exocrine secretions, including lacrimal fluid, saliva, and bile. Lactoferrin has been investigated for its numerous powerful influences, including anticancer, anti-inflammatory, anti-oxidant, anti-osteoporotic, antifungal, antibacterial, antiviral, immunomodulatory, hepatoprotective, and other beneficial health effects. Lactoferrin demonstrated several nutraceutical and pharmaceutical potentials and have a significant impact on improving the health of humans and animals. Lactoferrin plays a critical role in keeping the normal physiological homeostasis associated with the development of pathological disorders. The current review highlights the medicinal value, nutraceutical role, therapeutic application, and outstanding favorable health sides of lactoferrin, which would benefit from more exploration of this glycoprotein for the design of effective medicines, drugs, and pharmaceuticals for safeguarding different health issues in animals and humans. Springer US 2023-04-14 /pmc/articles/PMC10104436/ /pubmed/37059920 http://dx.doi.org/10.1007/s12011-023-03658-4 Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Ashraf, Muhammad Faizan
Zubair, Dawood
Bashir, Muhammad Noaman
Alagawany, Mahmoud
Ahmed, Shabbir
Shah, Qurban Ali
Buzdar, Jameel Ahmed
Arain, Muhammad Asif
Nutraceutical and Health-Promoting Potential of Lactoferrin, an Iron-Binding Protein in Human and Animal: Current Knowledge
title Nutraceutical and Health-Promoting Potential of Lactoferrin, an Iron-Binding Protein in Human and Animal: Current Knowledge
title_full Nutraceutical and Health-Promoting Potential of Lactoferrin, an Iron-Binding Protein in Human and Animal: Current Knowledge
title_fullStr Nutraceutical and Health-Promoting Potential of Lactoferrin, an Iron-Binding Protein in Human and Animal: Current Knowledge
title_full_unstemmed Nutraceutical and Health-Promoting Potential of Lactoferrin, an Iron-Binding Protein in Human and Animal: Current Knowledge
title_short Nutraceutical and Health-Promoting Potential of Lactoferrin, an Iron-Binding Protein in Human and Animal: Current Knowledge
title_sort nutraceutical and health-promoting potential of lactoferrin, an iron-binding protein in human and animal: current knowledge
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104436/
https://www.ncbi.nlm.nih.gov/pubmed/37059920
http://dx.doi.org/10.1007/s12011-023-03658-4
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