The moonlighting function of glycolytic enzyme enolase-1 promotes choline phospholipid metabolism and tumor cell proliferation

Aberrantly upregulated choline phospholipid metabolism is a novel emerging hallmark of cancer, and choline kinase α (CHKα), a key enzyme for phosphatidylcholine production, is overexpressed in many types of human cancer through undefined mechanisms. Here, we demonstrate that the expression levels of...

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Detalles Bibliográficos
Autores principales: Ma, Qingxia, Jiang, Hongfei, Ma, Leina, Zhao, Gaoxiang, Xu, Qianqian, Guo, Dong, He, Ningning, Liu, Hao, Meng, Zhaoyuan, Liu, Juanjuan, Zhu, Lei, Lin, Qian, Wu, Xiaolin, Li, Min, Luo, Shudi, Fang, Jing, Lu, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104498/
https://www.ncbi.nlm.nih.gov/pubmed/37011206
http://dx.doi.org/10.1073/pnas.2209435120

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