“Helicase” activity promoted through dynamic interactions between a ssDNA translocase and a diffusing SSB protein

Replication protein A (RPA) is a eukaryotic single-stranded (ss) DNA-binding (SSB) protein that is essential for all aspects of genome maintenance. RPA binds ssDNA with high affinity but can also diffuse along ssDNA. By itself, RPA is capable of transiently disrupting short regions of duplex DNA by...

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Detalles Bibliográficos
Autores principales: Mersch, Kacey N., Sokoloski, Joshua E., Nguyen, Binh, Galletto, Roberto, Lohman, Timothy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104510/
https://www.ncbi.nlm.nih.gov/pubmed/37011199
http://dx.doi.org/10.1073/pnas.2216777120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104510/
https://www.ncbi.nlm.nih.gov/pubmed/37011199
http://dx.doi.org/10.1073/pnas.2216777120

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