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Mutant β(1)-adrenergic receptor improves REM sleep and ameliorates tau accumulation in a mouse model of tauopathy

Sleep is essential for our well-being, and chronic sleep deprivation has unfavorable health consequences. We recently demonstrated that two familial natural short sleep (FNSS) mutations, DEC2-P384R and Npsr1-Y206H, are strong genetic modifiers of tauopathy in PS19 mice, a model of tauopathy. To gain...

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Detalles Bibliográficos
Autores principales:	Dong, Qing, Ptáček, Louis J., Fu, Ying-Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104526/ https://www.ncbi.nlm.nih.gov/pubmed/37014857 http://dx.doi.org/10.1073/pnas.2221686120

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