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High-throughput cryo-ET structural pattern mining by unsupervised deep iterative subtomogram clustering
Cryoelectron tomography directly visualizes heterogeneous macromolecular structures in their native and complex cellular environments. However, existing computer-assisted structure sorting approaches are low throughput or inherently limited due to their dependency on available templates and manual l...
Autores principales: | Zeng, Xiangrui, Kahng, Anson, Xue, Liang, Mahamid, Julia, Chang, Yi-Wei, Xu, Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104553/ https://www.ncbi.nlm.nih.gov/pubmed/37027429 http://dx.doi.org/10.1073/pnas.2213149120 |
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