Detection of rare mutations, copy number alterations, and methylation in the same template DNA molecules

The analysis of cell-free DNA (cfDNA) from plasma offers great promise for the earlier detection of cancer. At present, changes in DNA sequence, methylation, or copy number are the most sensitive ways to detect the presence of cancer. To further increase the sensitivity of such assays with limited a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yuxuan, Douville, Christopher, Cohen, Joshua D., Mattox, Austin, Curtis, Sam, Silliman, Natalie, Popoli, Maria, Ptak, Janine, Dobbyn, Lisa, Nehme, Nadine, Dudley, Jonathan C., Summers, Mahmoud, Zhang, Ming, Ho-Pham, Lan T., Tran, Bich N. H., Tran, Thach S., Nguyen, Tuan V., Bettegowda, Chetan, Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104560/
https://www.ncbi.nlm.nih.gov/pubmed/37014860
http://dx.doi.org/10.1073/pnas.2220704120

Ejemplares similares

Ejemplares similares