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NeuronMotif: Deciphering cis-regulatory codes by layer-wise demixing of deep neural networks
Discovering DNA regulatory sequence motifs and their relative positions is vital to understanding the mechanisms of gene expression regulation. Although deep convolutional neural networks (CNNs) have achieved great success in predicting cis-regulatory elements, the discovery of motifs and their comb...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104575/ https://www.ncbi.nlm.nih.gov/pubmed/37023129 http://dx.doi.org/10.1073/pnas.2216698120 |