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NeuronMotif: Deciphering cis-regulatory codes by layer-wise demixing of deep neural networks

Discovering DNA regulatory sequence motifs and their relative positions is vital to understanding the mechanisms of gene expression regulation. Although deep convolutional neural networks (CNNs) have achieved great success in predicting cis-regulatory elements, the discovery of motifs and their comb...

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Detalles Bibliográficos
Autores principales: Wei, Zheng, Hua, Kui, Wei, Lei, Ma, Shining, Jiang, Rui, Zhang, Xuegong, Li, Yanda, Wong, Wing H., Wang, Xiaowo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104575/
https://www.ncbi.nlm.nih.gov/pubmed/37023129
http://dx.doi.org/10.1073/pnas.2216698120

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