ETV4 Mediated Tumor‐Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer (Adv. Sci. 11/2023)

Tumor‐Associated Neutrophil In article number 2205613, Xu Chen, Tianxin Lin, and co‐workers reveal a novel mechanism of tumor‐associated neutrophil (TANs) in lymph node (LN)‐metastatic bladder cancer. ETS variant transcription factor (ETV4) enhances bladder cancer (BCa) cells‐derived chemokine C‐X‐C...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qiang, Liu, Sen, Wang, Hongjin, Xiao, Kanghua, Lu, Junlin, Chen, Siting, Huang, Ming, Xie, Ruihui, Lin, Tianxin, Chen, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Inside Back Cover
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104622/
http://dx.doi.org/10.1002/advs.202370065
_version_ 1785026074615218176
author Zhang, Qiang
Liu, Sen
Wang, Hongjin
Xiao, Kanghua
Lu, Junlin
Chen, Siting
Huang, Ming
Xie, Ruihui
Lin, Tianxin
Chen, Xu
author_facet Zhang, Qiang
Liu, Sen
Wang, Hongjin
Xiao, Kanghua
Lu, Junlin
Chen, Siting
Huang, Ming
Xie, Ruihui
Lin, Tianxin
Chen, Xu
author_sort Zhang, Qiang
collection PubMed
description Tumor‐Associated Neutrophil In article number 2205613, Xu Chen, Tianxin Lin, and co‐workers reveal a novel mechanism of tumor‐associated neutrophil (TANs) in lymph node (LN)‐metastatic bladder cancer. ETS variant transcription factor (ETV4) enhances bladder cancer (BCa) cells‐derived chemokine C‐X‐C motif ligand (CXCL)1/8 to recruit TANs, leading to the increase of vascular endothelial growth factor A (VEGFA) and matrix metalloproteinase‐9 (MMP9), and then facilitating lymphangiogenesis and LN metastasis of bladder cancer. [Image: see text]
format Online
Article
Text
id pubmed-10104622
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-101046222023-04-15 ETV4 Mediated Tumor‐Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer (Adv. Sci. 11/2023) Zhang, Qiang Liu, Sen Wang, Hongjin Xiao, Kanghua Lu, Junlin Chen, Siting Huang, Ming Xie, Ruihui Lin, Tianxin Chen, Xu Adv Sci (Weinh) Inside Back Cover Tumor‐Associated Neutrophil In article number 2205613, Xu Chen, Tianxin Lin, and co‐workers reveal a novel mechanism of tumor‐associated neutrophil (TANs) in lymph node (LN)‐metastatic bladder cancer. ETS variant transcription factor (ETV4) enhances bladder cancer (BCa) cells‐derived chemokine C‐X‐C motif ligand (CXCL)1/8 to recruit TANs, leading to the increase of vascular endothelial growth factor A (VEGFA) and matrix metalloproteinase‐9 (MMP9), and then facilitating lymphangiogenesis and LN metastasis of bladder cancer. [Image: see text] John Wiley and Sons Inc. 2023-04-14 /pmc/articles/PMC10104622/ http://dx.doi.org/10.1002/advs.202370065 Text en © 2023 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Inside Back Cover
Zhang, Qiang
Liu, Sen
Wang, Hongjin
Xiao, Kanghua
Lu, Junlin
Chen, Siting
Huang, Ming
Xie, Ruihui
Lin, Tianxin
Chen, Xu
ETV4 Mediated Tumor‐Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer (Adv. Sci. 11/2023)
title ETV4 Mediated Tumor‐Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer (Adv. Sci. 11/2023)
title_full ETV4 Mediated Tumor‐Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer (Adv. Sci. 11/2023)
title_fullStr ETV4 Mediated Tumor‐Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer (Adv. Sci. 11/2023)
title_full_unstemmed ETV4 Mediated Tumor‐Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer (Adv. Sci. 11/2023)
title_short ETV4 Mediated Tumor‐Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer (Adv. Sci. 11/2023)
title_sort etv4 mediated tumor‐associated neutrophil infiltration facilitates lymphangiogenesis and lymphatic metastasis of bladder cancer (adv. sci. 11/2023)
topic Inside Back Cover
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104622/
http://dx.doi.org/10.1002/advs.202370065
work_keys_str_mv AT zhangqiang etv4mediatedtumorassociatedneutrophilinfiltrationfacilitateslymphangiogenesisandlymphaticmetastasisofbladdercanceradvsci112023
AT liusen etv4mediatedtumorassociatedneutrophilinfiltrationfacilitateslymphangiogenesisandlymphaticmetastasisofbladdercanceradvsci112023
AT wanghongjin etv4mediatedtumorassociatedneutrophilinfiltrationfacilitateslymphangiogenesisandlymphaticmetastasisofbladdercanceradvsci112023
AT xiaokanghua etv4mediatedtumorassociatedneutrophilinfiltrationfacilitateslymphangiogenesisandlymphaticmetastasisofbladdercanceradvsci112023
AT lujunlin etv4mediatedtumorassociatedneutrophilinfiltrationfacilitateslymphangiogenesisandlymphaticmetastasisofbladdercanceradvsci112023
AT chensiting etv4mediatedtumorassociatedneutrophilinfiltrationfacilitateslymphangiogenesisandlymphaticmetastasisofbladdercanceradvsci112023
AT huangming etv4mediatedtumorassociatedneutrophilinfiltrationfacilitateslymphangiogenesisandlymphaticmetastasisofbladdercanceradvsci112023
AT xieruihui etv4mediatedtumorassociatedneutrophilinfiltrationfacilitateslymphangiogenesisandlymphaticmetastasisofbladdercanceradvsci112023
AT lintianxin etv4mediatedtumorassociatedneutrophilinfiltrationfacilitateslymphangiogenesisandlymphaticmetastasisofbladdercanceradvsci112023
AT chenxu etv4mediatedtumorassociatedneutrophilinfiltrationfacilitateslymphangiogenesisandlymphaticmetastasisofbladdercanceradvsci112023

Ejemplares similares