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Enabling Single‐Cell Drug Response Annotations from Bulk RNA‐Seq Using SCAD

The single‐cell RNA sequencing (scRNA‐seq) quantifies the gene expression of individual cells, while the bulk RNA sequencing (bulk RNA‐seq) characterizes the mixed transcriptome of cells. The inference of drug sensitivities for individual cells can provide new insights to understand the mechanism of...

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Detalles Bibliográficos
Autores principales: Zheng, Zetian, Chen, Junyi, Chen, Xingjian, Huang, Lei, Xie, Weidun, Lin, Qiuzhen, Li, Xiangtao, Wong, Ka‐Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104628/
https://www.ncbi.nlm.nih.gov/pubmed/36762572
http://dx.doi.org/10.1002/advs.202204113