Loss of RPA1 Impairs Peripheral T Cell Homeostasis and Exacerbates Inflammatory Damage through Triggering T Cell Necroptosis

The peripheral T cell pool is maintained at dynamic homeostasis through fine‐tuning of thymic output and self‐renewal of naïve T cells. Lymphopenia or reduced lymphocyte number is implicated in autoimmune diseases, yet little is known about the homeostatic mechanisms. Here, it is reported that the r...

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Detalles Bibliográficos
Autores principales: Song, Jia, Zhang, Xin, Yin, Yue, Guo, Mengfan, Zhao, Xuyang, Wang, Likun, Ren, Caixia, Yin, Yuxin, Zhang, Xuehui, Deng, Xuliang, Lu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104672/
https://www.ncbi.nlm.nih.gov/pubmed/36721037
http://dx.doi.org/10.1002/advs.202206344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104672/
https://www.ncbi.nlm.nih.gov/pubmed/36721037
http://dx.doi.org/10.1002/advs.202206344

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