Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment

An 80-year-old woman underwent pancreatoduodenectomy. Post-operation, she experienced a fever, and a culture of blood revealed metallo-beta-lactamase-producing Raoultella ornithinolytica. For treatments with aminoglycoside antimicrobial agents, a therapeutic drug monitoring-based dosing design can l...

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Autores principales: Koishi, Noriko, Sasano, Hiroshi, Yoshizawa, Toshihiro, Shikuri, Mika, Matsumoto, Hiroshi, Suzuki, Mai, Fukui, Yukiko, Chonan, Masayoshi, Kimura, Toshimi, Ichida, Hirofumi, Saiura, Akio, Naito, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104729/
https://www.ncbi.nlm.nih.gov/pubmed/37065978
http://dx.doi.org/10.1155/2023/5574769
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author Koishi, Noriko
Sasano, Hiroshi
Yoshizawa, Toshihiro
Shikuri, Mika
Matsumoto, Hiroshi
Suzuki, Mai
Fukui, Yukiko
Chonan, Masayoshi
Kimura, Toshimi
Ichida, Hirofumi
Saiura, Akio
Naito, Toshio
author_facet Koishi, Noriko
Sasano, Hiroshi
Yoshizawa, Toshihiro
Shikuri, Mika
Matsumoto, Hiroshi
Suzuki, Mai
Fukui, Yukiko
Chonan, Masayoshi
Kimura, Toshimi
Ichida, Hirofumi
Saiura, Akio
Naito, Toshio
author_sort Koishi, Noriko
collection PubMed
description An 80-year-old woman underwent pancreatoduodenectomy. Post-operation, she experienced a fever, and a culture of blood revealed metallo-beta-lactamase-producing Raoultella ornithinolytica. For treatments with aminoglycoside antimicrobial agents, a therapeutic drug monitoring-based dosing design can lower the risk of adverse events and enable appropriate treatment. Key Clinical Message. When aminoglycoside antimicrobial agents are administered for MBL-producing bacteremia, prescription suggestions based on TDM by antimicrobial stewardship team can reduce the occurrence of adverse events and enable appropriate treatment.
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spelling pubmed-101047292023-04-15 Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment Koishi, Noriko Sasano, Hiroshi Yoshizawa, Toshihiro Shikuri, Mika Matsumoto, Hiroshi Suzuki, Mai Fukui, Yukiko Chonan, Masayoshi Kimura, Toshimi Ichida, Hirofumi Saiura, Akio Naito, Toshio Case Rep Infect Dis Case Report An 80-year-old woman underwent pancreatoduodenectomy. Post-operation, she experienced a fever, and a culture of blood revealed metallo-beta-lactamase-producing Raoultella ornithinolytica. For treatments with aminoglycoside antimicrobial agents, a therapeutic drug monitoring-based dosing design can lower the risk of adverse events and enable appropriate treatment. Key Clinical Message. When aminoglycoside antimicrobial agents are administered for MBL-producing bacteremia, prescription suggestions based on TDM by antimicrobial stewardship team can reduce the occurrence of adverse events and enable appropriate treatment. Hindawi 2023-04-07 /pmc/articles/PMC10104729/ /pubmed/37065978 http://dx.doi.org/10.1155/2023/5574769 Text en Copyright © 2023 Noriko Koishi et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Koishi, Noriko
Sasano, Hiroshi
Yoshizawa, Toshihiro
Shikuri, Mika
Matsumoto, Hiroshi
Suzuki, Mai
Fukui, Yukiko
Chonan, Masayoshi
Kimura, Toshimi
Ichida, Hirofumi
Saiura, Akio
Naito, Toshio
Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment
title Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment
title_full Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment
title_fullStr Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment
title_full_unstemmed Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment
title_short Successful Treatment of a Case of Metallo-Beta-Lactamase-Producing Raoultella ornithinolytica Bacteremia by Antimicrobial Stewardship Team Intervention and Therapeutic Drug Monitoring-Based Amikacin Treatment
title_sort successful treatment of a case of metallo-beta-lactamase-producing raoultella ornithinolytica bacteremia by antimicrobial stewardship team intervention and therapeutic drug monitoring-based amikacin treatment
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104729/
https://www.ncbi.nlm.nih.gov/pubmed/37065978
http://dx.doi.org/10.1155/2023/5574769
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