Dynamic antagonism between key repressive pathways maintains the placental epigenome

DNA and Histone 3 Lysine 27 methylation typically function as repressive modifications and operate within distinct genomic compartments. In mammals, the majority of the genome is kept in a DNA methylated state, whereas the Polycomb repressive complexes regulate the unmethylated CpG-rich promoters of...

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Detalles Bibliográficos
Autores principales: Weigert, Raha, Hetzel, Sara, Bailly, Nina, Haggerty, Chuck, Ilik, Ibrahim A., Yung, Philip Yuk Kwong, Navarro, Carmen, Bolondi, Adriano, Kumar, Abhishek Sampath, Anania, Chiara, Brändl, Björn, Meierhofer, David, Lupiáñez, Darío G., Müller, Franz-Josef, Aktas, Tugce, Elsässer, Simon J., Kretzmer, Helene, Smith, Zachary D., Meissner, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104784/
https://www.ncbi.nlm.nih.gov/pubmed/37024684
http://dx.doi.org/10.1038/s41556-023-01114-y

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