Cargando…
Oncogenic drivers dictate immune control of acute myeloid leukemia
Acute myeloid leukemia (AML) is a genetically heterogeneous, aggressive hematological malignancy induced by distinct oncogenic driver mutations. The effect of specific AML oncogenes on immune activation or suppression is unclear. Here, we examine immune responses in genetically distinct models of AM...
Autores principales: | Austin, Rebecca J., Straube, Jasmin, Halder, Rohit, Janardhanan, Yashaswini, Bruedigam, Claudia, Witkowski, Matthew, Cooper, Leanne, Porter, Amy, Braun, Matthias, Souza-Fonseca-Guimaraes, Fernando, Minnie, Simone A., Cooper, Emily, Jacquelin, Sebastien, Song, Axia, Bald, Tobias, Nakamura, Kyohei, Hill, Geoffrey R., Aifantis, Iannis, Lane, Steven W., Bywater, Megan J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104832/ https://www.ncbi.nlm.nih.gov/pubmed/37059710 http://dx.doi.org/10.1038/s41467-023-37592-9 |
Ejemplares similares
-
Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia
por: Straube, Jasmin, et al.
Publicado: (2023) -
Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia
por: Vu, Therese, et al.
Publicado: (2020) -
MPN: The Molecular Drivers of Disease Initiation, Progression and Transformation and their Effect on Treatment
por: Grabek, Julian, et al.
Publicado: (2020) -
Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think
por: Lobry, Camille, et al.
Publicado: (2011) -
Mapping and targeting of the leukemic microenvironment
por: Witkowski, Matthew T., et al.
Publicado: (2019)