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Legionella para-effectors target chromatin and promote bacterial replication

Legionella pneumophila replicates intracellularly by secreting effectors via a type IV secretion system. One of these effectors is a eukaryotic methyltransferase (RomA) that methylates K14 of histone H3 (H3K14me3) to counteract host immune responses. However, it is not known how L. pneumophila infec...

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Detalles Bibliográficos
Autores principales: Schator, Daniel, Mondino, Sonia, Berthelet, Jérémy, Di Silvestre, Cristina, Ben Assaya, Mathilde, Rusniok, Christophe, Rodrigues-Lima, Fernando, Wehenkel, Annemarie, Buchrieser, Carmen, Rolando, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104843/
https://www.ncbi.nlm.nih.gov/pubmed/37059817
http://dx.doi.org/10.1038/s41467-023-37885-z