ALAN is a computational approach that interprets genomic findings in the context of tumor ecosystems

Gene behavior is governed by activity of other genes in an ecosystem as well as context-specific cues including cell type, microenvironment, and prior exposure to therapy. Here, we developed the Algorithm for Linking Activity Networks (ALAN) to compare gene behavior purely based on patient -omic dat...

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Detalles Bibliográficos
Autores principales: Bergom, Hannah E., Shabaneh, Ashraf, Day, Abderrahman, Ali, Atef, Boytim, Ella, Tape, Sydney, Lozada, John R., Shi, Xiaolei, Kerkvliet, Carlos Perez, McSweeney, Sean, Pitzen, Samuel P., Ludwig, Megan, Antonarakis, Emmanuel S., Drake, Justin M., Dehm, Scott M., Ryan, Charles J., Wang, Jinhua, Hwang, Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104859/
https://www.ncbi.nlm.nih.gov/pubmed/37059746
http://dx.doi.org/10.1038/s42003-023-04795-1

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