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Lysosomal lipid peroxidation mediates immunogenic cell death
Cancer cells rely on lysosome-dependent degradation to recycle nutrients that serve their energetic and biosynthetic needs. Despite great interest in repurposing the antimalarial hydroxychloroquine as a lysosomal inhibitor in clinical oncology trials, the mechanisms by which hydroxychloroquine and o...
Autores principales: | Phadatare, Pravin, Debnath, Jayanta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104885/ https://www.ncbi.nlm.nih.gov/pubmed/37066873 http://dx.doi.org/10.1172/JCI169240 |
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