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Deconstructing cellular senescence in bone and beyond
Osteocytes are specialized bone cells that orchestrate skeletal remodeling. Senescent osteocytes are characterized by an activation of cyclin-dependent kinase inhibitor p16(Ink4a) and have been implicated in the pathogenesis of several bone loss disorders. In this issue of the JCI, Farr et al. have...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Clinical Investigation
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104887/ https://www.ncbi.nlm.nih.gov/pubmed/37066877 http://dx.doi.org/10.1172/JCI169069 |