Lysosomal lipid peroxidation regulates tumor immunity

Lysosomal inhibition elicited by palmitoyl-protein thioesterase 1 (PPT1) inhibitors such as DC661 can produce cell death, but the mechanism for this is not completely understood. Programmed cell death pathways (autophagy, apoptosis, necroptosis, ferroptosis, and pyroptosis) were not required to achi...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhardwaj, Monika, Lee, Jennifer J., Versace, Amanda M., Harper, Sandra L., Goldman, Aaron R., Crissey, Mary Ann S., Jain, Vaibhav, Singh, Mahendra Pal, Vernon, Megane, Aplin, Andrew E., Lee, Seokwoo, Morita, Masao, Winkler, Jeffrey D., Liu, Qin, Speicher, David W., Amaravadi, Ravi K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10104903/
https://www.ncbi.nlm.nih.gov/pubmed/36795483
http://dx.doi.org/10.1172/JCI164596

Ejemplares similares

Ejemplares similares