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Incidence of SARS-CoV-2 Co-infections During the Second Wave in Sub-Himalayan Region, India

Introduction The second wave of the coronavirus disease 2019 (COVID-19) pandemic in India, which started from April 2021, has been more severe and deadly than the first wave. The aim of this prospective study was to determine the possibility of other respiratory pathogens contributing towards the se...

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Autores principales: Gupta, Shailesh, Negi, Ashish, Negi, Shailender, Diksha, Diksha, Kandwal, Diksha, Singh, Arpana, Singh, Anshu, Gupta, Pratima, Kalita, Deepjyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105344/
https://www.ncbi.nlm.nih.gov/pubmed/37069862
http://dx.doi.org/10.7759/cureus.36215
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author Gupta, Shailesh
Negi, Ashish
Negi, Shailender
Diksha, Diksha
Kandwal, Diksha
Singh, Arpana
Singh, Anshu
Gupta, Pratima
Kalita, Deepjyoti
author_facet Gupta, Shailesh
Negi, Ashish
Negi, Shailender
Diksha, Diksha
Kandwal, Diksha
Singh, Arpana
Singh, Anshu
Gupta, Pratima
Kalita, Deepjyoti
author_sort Gupta, Shailesh
collection PubMed
description Introduction The second wave of the coronavirus disease 2019 (COVID-19) pandemic in India, which started from April 2021, has been more severe and deadly than the first wave. The aim of this prospective study was to determine the possibility of other respiratory pathogens contributing towards the severity and hospitalization in the current second wave. Materials and methods Nasopharyngeal and oropharyngeal swab samples were collected and processed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by reverse transcription polymerase chain reaction (RT-PCR). These samples were further processed for detection of co-infection in SARS CoV-2 patients by BioFire® Filmarray® 2.0 (bioMérieux, USA). Results We screened 77 COVID-19-positive patients admitted to All India Institute of Medical Sciences (AIIMS), Rishikesh and found cases of co-infections in five (6.49 %) patients. Conclusion Our finding suggests that co-infections had no or minimal role in augmenting the second wave of the COVID-19 pandemic in India, and the emergence of new variants may be the probable cause.
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spelling pubmed-101053442023-04-16 Incidence of SARS-CoV-2 Co-infections During the Second Wave in Sub-Himalayan Region, India Gupta, Shailesh Negi, Ashish Negi, Shailender Diksha, Diksha Kandwal, Diksha Singh, Arpana Singh, Anshu Gupta, Pratima Kalita, Deepjyoti Cureus Infectious Disease Introduction The second wave of the coronavirus disease 2019 (COVID-19) pandemic in India, which started from April 2021, has been more severe and deadly than the first wave. The aim of this prospective study was to determine the possibility of other respiratory pathogens contributing towards the severity and hospitalization in the current second wave. Materials and methods Nasopharyngeal and oropharyngeal swab samples were collected and processed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by reverse transcription polymerase chain reaction (RT-PCR). These samples were further processed for detection of co-infection in SARS CoV-2 patients by BioFire® Filmarray® 2.0 (bioMérieux, USA). Results We screened 77 COVID-19-positive patients admitted to All India Institute of Medical Sciences (AIIMS), Rishikesh and found cases of co-infections in five (6.49 %) patients. Conclusion Our finding suggests that co-infections had no or minimal role in augmenting the second wave of the COVID-19 pandemic in India, and the emergence of new variants may be the probable cause. Cureus 2023-03-16 /pmc/articles/PMC10105344/ /pubmed/37069862 http://dx.doi.org/10.7759/cureus.36215 Text en Copyright © 2023, Gupta et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Infectious Disease
Gupta, Shailesh
Negi, Ashish
Negi, Shailender
Diksha, Diksha
Kandwal, Diksha
Singh, Arpana
Singh, Anshu
Gupta, Pratima
Kalita, Deepjyoti
Incidence of SARS-CoV-2 Co-infections During the Second Wave in Sub-Himalayan Region, India
title Incidence of SARS-CoV-2 Co-infections During the Second Wave in Sub-Himalayan Region, India
title_full Incidence of SARS-CoV-2 Co-infections During the Second Wave in Sub-Himalayan Region, India
title_fullStr Incidence of SARS-CoV-2 Co-infections During the Second Wave in Sub-Himalayan Region, India
title_full_unstemmed Incidence of SARS-CoV-2 Co-infections During the Second Wave in Sub-Himalayan Region, India
title_short Incidence of SARS-CoV-2 Co-infections During the Second Wave in Sub-Himalayan Region, India
title_sort incidence of sars-cov-2 co-infections during the second wave in sub-himalayan region, india
topic Infectious Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105344/
https://www.ncbi.nlm.nih.gov/pubmed/37069862
http://dx.doi.org/10.7759/cureus.36215
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