Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19

Effective humoral immune responses require well-orchestrated B and T follicular helper (Tfh) cell interactions. Whether these interactions are impaired and associated with COVID-19 disease severity is unclear. Here, longitudinal blood samples across COVID-19 disease severity are analysed. We find th...

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Detalles Bibliográficos
Autores principales: Yu, Meng, Charles, Afandi, Cagigi, Alberto, Christ, Wanda, Österberg, Björn, Falck-Jones, Sara, Azizmohammadi, Lida, Åhlberg, Eric, Falck-Jones, Ryan, Svensson, Julia, Nie, Mu, Warnqvist, Anna, Hellgren, Fredrika, Lenart, Klara, Arcoverde Cerveira, Rodrigo, Ols, Sebastian, Lindgren, Gustaf, Lin, Ang, Maecker, Holden, Bell, Max, Johansson, Niclas, Albert, Jan, Sundling, Christopher, Czarnewski, Paulo, Klingström, Jonas, Färnert, Anna, Loré, Karin, Smed-Sörensen, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105364/
https://www.ncbi.nlm.nih.gov/pubmed/37061513
http://dx.doi.org/10.1038/s41467-023-37835-9

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