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Excessive exogenous cholesterol activating intestinal LXRα-ABCA1/G5/G8 signaling pathway can not reverse atherosclerosis in ApoE(−/−) mice

BACKGROUND: The long-term excessive intake of exogenous cholesterol can lead to abnormally elevated blood lipid levels and induce cardiovascular and cerebrovascular diseases. However, the influence and relevance of exogenous cholesterol on plasma cholesterol components were still unclear, and the in...

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Detalles Bibliográficos
Autores principales: Yu, Xichao, Ding, Xue, Feng, Han, Bi, Yunhui, Li, Yu, Shan, Jinjun, Bian, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105390/
https://www.ncbi.nlm.nih.gov/pubmed/37061692
http://dx.doi.org/10.1186/s12944-023-01810-6