Notch signaling is activated in knee-innervating dorsal root ganglia in experimental models of osteoarthritis joint pain

BACKGROUND: We aimed to explore activation of the Notch signaling pathway in knee-innervating lumbar dorsal root ganglia (DRG) in the course of experimental osteoarthritis (OA) in mice, and its role in knee hyperalgesia. METHODS: Cultured DRG cells were stimulated with the TLR4 agonist, lipopolysacc...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Lai, Ishihara, Shingo, Li, Jun, Miller, Rachel E., Malfait, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105425/
https://www.ncbi.nlm.nih.gov/pubmed/37061736
http://dx.doi.org/10.1186/s13075-023-03039-1

Ejemplares similares

Ejemplares similares