Cargando…
Whole-genome sequencing for surveillance of antimicrobial resistance in Ecuador: present and future implications
Whole-genome sequencing is becoming the gold standard for pathogen characterization and offers considerable advantages for understanding the evolution and dissemination of new determinants of antimicrobial resistance. Despite the benefits of whole-genome sequencing for pathogen characterization, imp...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Organización Panamericana de la Salud
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105595/ https://www.ncbi.nlm.nih.gov/pubmed/37082537 http://dx.doi.org/10.26633/RPSP.2023.8 |
_version_ | 1785026244717314048 |
---|---|
author | Calero-Cáceres, William Ortuño-Gutiérrez, Nimer Sunyoto, Temmy Gomes-Dias, Cícero-Armídio Bastidas-Caldes, Carlos Ramírez, Ma. Soledad Harries, Anthony D. |
author_facet | Calero-Cáceres, William Ortuño-Gutiérrez, Nimer Sunyoto, Temmy Gomes-Dias, Cícero-Armídio Bastidas-Caldes, Carlos Ramírez, Ma. Soledad Harries, Anthony D. |
author_sort | Calero-Cáceres, William |
collection | PubMed |
description | Whole-genome sequencing is becoming the gold standard for pathogen characterization and offers considerable advantages for understanding the evolution and dissemination of new determinants of antimicrobial resistance. Despite the benefits of whole-genome sequencing for pathogen characterization, implementation costs and lack of expertise may limit its use by public health laboratories. This article reviews the advantages of whole-genome sequencing for pathogen characterization and the current status of the use of whole-genome sequencing for antimicrobial resistance surveillance in Ecuador. A roadmap is suggested for including whole-genome sequencing for pathogen characterization based on the needs of the health reference institutions through alliances with Ecuadorian universities. Establishing a partnership between public health institutions and academia would be valuable for clinicians, policy-makers, and epidemiologists who could then take reasonable measures in those areas and establish a basis for adapting One Health strategies to tackle antimicrobial resistance in Ecuador. |
format | Online Article Text |
id | pubmed-10105595 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Organización Panamericana de la Salud |
record_format | MEDLINE/PubMed |
spelling | pubmed-101055952023-04-19 Whole-genome sequencing for surveillance of antimicrobial resistance in Ecuador: present and future implications Calero-Cáceres, William Ortuño-Gutiérrez, Nimer Sunyoto, Temmy Gomes-Dias, Cícero-Armídio Bastidas-Caldes, Carlos Ramírez, Ma. Soledad Harries, Anthony D. Rev Panam Salud Publica Opinion and Analysis Whole-genome sequencing is becoming the gold standard for pathogen characterization and offers considerable advantages for understanding the evolution and dissemination of new determinants of antimicrobial resistance. Despite the benefits of whole-genome sequencing for pathogen characterization, implementation costs and lack of expertise may limit its use by public health laboratories. This article reviews the advantages of whole-genome sequencing for pathogen characterization and the current status of the use of whole-genome sequencing for antimicrobial resistance surveillance in Ecuador. A roadmap is suggested for including whole-genome sequencing for pathogen characterization based on the needs of the health reference institutions through alliances with Ecuadorian universities. Establishing a partnership between public health institutions and academia would be valuable for clinicians, policy-makers, and epidemiologists who could then take reasonable measures in those areas and establish a basis for adapting One Health strategies to tackle antimicrobial resistance in Ecuador. Organización Panamericana de la Salud 2023-04-19 /pmc/articles/PMC10105595/ /pubmed/37082537 http://dx.doi.org/10.26633/RPSP.2023.8 Text en https://creativecommons.org/licenses/by-nc-nd/3.0/us/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 IGO License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited. No modifications or commercial use of this article are permitted. In any reproduction of this article there should not be any suggestion that PAHO or this article endorse any specific organization or products. The use of the PAHO logo is not permitted. This notice should be preserved along with the article’s original URL. Open access logo and text by PLoS, under the Creative Commons Attribution-Share Alike 3.0 Unported license. |
spellingShingle | Opinion and Analysis Calero-Cáceres, William Ortuño-Gutiérrez, Nimer Sunyoto, Temmy Gomes-Dias, Cícero-Armídio Bastidas-Caldes, Carlos Ramírez, Ma. Soledad Harries, Anthony D. Whole-genome sequencing for surveillance of antimicrobial resistance in Ecuador: present and future implications |
title | Whole-genome sequencing for surveillance of antimicrobial resistance in Ecuador: present and future implications |
title_full | Whole-genome sequencing for surveillance of antimicrobial resistance in Ecuador: present and future implications |
title_fullStr | Whole-genome sequencing for surveillance of antimicrobial resistance in Ecuador: present and future implications |
title_full_unstemmed | Whole-genome sequencing for surveillance of antimicrobial resistance in Ecuador: present and future implications |
title_short | Whole-genome sequencing for surveillance of antimicrobial resistance in Ecuador: present and future implications |
title_sort | whole-genome sequencing for surveillance of antimicrobial resistance in ecuador: present and future implications |
topic | Opinion and Analysis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105595/ https://www.ncbi.nlm.nih.gov/pubmed/37082537 http://dx.doi.org/10.26633/RPSP.2023.8 |
work_keys_str_mv | AT calerocacereswilliam wholegenomesequencingforsurveillanceofantimicrobialresistanceinecuadorpresentandfutureimplications AT ortunogutierreznimer wholegenomesequencingforsurveillanceofantimicrobialresistanceinecuadorpresentandfutureimplications AT sunyototemmy wholegenomesequencingforsurveillanceofantimicrobialresistanceinecuadorpresentandfutureimplications AT gomesdiasciceroarmidio wholegenomesequencingforsurveillanceofantimicrobialresistanceinecuadorpresentandfutureimplications AT bastidascaldescarlos wholegenomesequencingforsurveillanceofantimicrobialresistanceinecuadorpresentandfutureimplications AT ramirezmasoledad wholegenomesequencingforsurveillanceofantimicrobialresistanceinecuadorpresentandfutureimplications AT harriesanthonyd wholegenomesequencingforsurveillanceofantimicrobialresistanceinecuadorpresentandfutureimplications |