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Population-based sero-epidemiological investigation of SARS-CoV-2 infection in Somalia

OBJECTIVES: To explore the burden of coronavirus disease 2019 (COVID-19) in Somalia by measuring the seroprevalence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the general population. METHODS: We recruited a convenience sample of 2751 participants from among indi...

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Detalles Bibliográficos
Autores principales: Hossain, Md Shajib, Derrow, Mohamed Mohamud, Mohamed, Sahra Isse, Abukar, Hasan Mukhtar, Qayad, Mohamed G., Malik, Sk Md Mamunur Rahman, Mengistu, Kumlachew Fikremariam, Obsie, Ali Abdilahi Ali, Anwar, Iqbal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105620/
https://www.ncbi.nlm.nih.gov/pubmed/37094495
http://dx.doi.org/10.1016/j.jiph.2023.04.016
Descripción
Sumario:OBJECTIVES: To explore the burden of coronavirus disease 2019 (COVID-19) in Somalia by measuring the seroprevalence of antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the general population. METHODS: We recruited a convenience sample of 2751 participants from among individuals attending outpatient and inpatient departments of public health facilities, or their accompanying family members. Participants were interviewed to collect sociodemographic data and provided a blood sample. We calculated seropositivity rates overall and by sex, age group, state, residence, education and marital status. We used logistic regression analysis – odds ratios and 95% confidence intervals (CI) – to investigate sociodemographic correlates of seropositivity. RESULTS: The overall seropositivity rate was 56.4% (95% CI 54.5–58.3%), while 8.8% of participants reported being previously diagnosed with COVID-19 by July 2021. In the regression analysis, after controlling for covariates, urban residence was significantly asscoiated with seropositivity: OR = 1.74 (95% CI: 1.19–2.55). CONCLUSIONS: Our results show a high seroprevalence rate of SARS-CoV-2 in the Somali population (56.4%), and indicate that many infections have not been captured by the country’s surveillance system resulting in considerable under-reporting.