β-Propiolactone (BPL)-inactivation of SARS-Co-V-2: In vitro validation with focus on saliva from COVID-19 patients for scent dog training

β-Propiolactone (BPL) is an organic compound widely used as an inactivating agent in vaccine development and production, for example for SARS-CoV, SARS-CoV-2 and Influenza viruses. Inactivation of pathogens by BPL is based on an irreversible alkylation of nucleic acids but also on acetylation and cr...

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Detalles Bibliográficos
Autores principales: Pilchová, Veronika, Prajeeth, Chittappen Kandiyil, Jendrny, Paula, Twele, Friederike, Meller, Sebastian, Pink, Isabell, Fathi, Anahita, Addo, Marylyn Martina, Volk, Holger Andreas, Osterhaus, Albert, von Köckritz-Blickwede, Maren, Schulz, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Protocols
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105625/
https://www.ncbi.nlm.nih.gov/pubmed/37068591
http://dx.doi.org/10.1016/j.jviromet.2023.114733

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