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Female urethroplasty with dorsal onlay buccal mucosal graft: a single institution experience

PURPOSE: Female urethral stricture disease is frequently unrecognized or misdiagnosed, with controversy in the literature regarding the definition of strictures and approach to management. The purpose of this study is to report our institutional experience with female urethroplasty and add our exper...

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Autores principales: Higgins, Margaret M., Wengryn, Derek, Koslov, David, Oliver, Janine, Flynn, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105657/
https://www.ncbi.nlm.nih.gov/pubmed/36859624
http://dx.doi.org/10.1007/s11255-023-03520-5
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author Higgins, Margaret M.
Wengryn, Derek
Koslov, David
Oliver, Janine
Flynn, Brian J.
author_facet Higgins, Margaret M.
Wengryn, Derek
Koslov, David
Oliver, Janine
Flynn, Brian J.
author_sort Higgins, Margaret M.
collection PubMed
description PURPOSE: Female urethral stricture disease is frequently unrecognized or misdiagnosed, with controversy in the literature regarding the definition of strictures and approach to management. The purpose of this study is to report our institutional experience with female urethroplasty and add our experience to the growing body of research. METHODS: We performed a retrospective review of patients undergoing female urethroplasty with dorsal onlay BMG at the University of Colorado between March 2015 and December 2021 performed by two surgeons (BF and JO). The primary outcome measure was surgical success, defined as no stricture recurrence. The secondary outcome measure was the incidence of de novo urinary incontinence. RESULTS: 23 patients were included in our data analysis. The median duration of lower urinary tract symptoms prior to urethroplasty was 16 years. 87% had undergone previous dilations. At a median follow-up of 12.2 months (range 1–81 months), four patients required a secondary procedure for obstruction with an overall success rate of 83%. One patient developed de novo stress urinary incontinence and one patient developed urge urinary incontinence. Subgroup analysis was performed comparing the patients that developed stricture recurrence (N = 4) to those that did not (N = 19). Those with stricture recurrence had a longer duration of symptoms and more dilations prior to urethroplasty. CONCLUSION: Female urethroplasty with BMG is effective at treating female urethral stricture disease, with excellent outcomes at over a year of follow-up and minimal risk of stress incontinence postoperatively.
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spelling pubmed-101056572023-04-17 Female urethroplasty with dorsal onlay buccal mucosal graft: a single institution experience Higgins, Margaret M. Wengryn, Derek Koslov, David Oliver, Janine Flynn, Brian J. Int Urol Nephrol Urology - Original Paper PURPOSE: Female urethral stricture disease is frequently unrecognized or misdiagnosed, with controversy in the literature regarding the definition of strictures and approach to management. The purpose of this study is to report our institutional experience with female urethroplasty and add our experience to the growing body of research. METHODS: We performed a retrospective review of patients undergoing female urethroplasty with dorsal onlay BMG at the University of Colorado between March 2015 and December 2021 performed by two surgeons (BF and JO). The primary outcome measure was surgical success, defined as no stricture recurrence. The secondary outcome measure was the incidence of de novo urinary incontinence. RESULTS: 23 patients were included in our data analysis. The median duration of lower urinary tract symptoms prior to urethroplasty was 16 years. 87% had undergone previous dilations. At a median follow-up of 12.2 months (range 1–81 months), four patients required a secondary procedure for obstruction with an overall success rate of 83%. One patient developed de novo stress urinary incontinence and one patient developed urge urinary incontinence. Subgroup analysis was performed comparing the patients that developed stricture recurrence (N = 4) to those that did not (N = 19). Those with stricture recurrence had a longer duration of symptoms and more dilations prior to urethroplasty. CONCLUSION: Female urethroplasty with BMG is effective at treating female urethral stricture disease, with excellent outcomes at over a year of follow-up and minimal risk of stress incontinence postoperatively. Springer Netherlands 2023-03-01 2023 /pmc/articles/PMC10105657/ /pubmed/36859624 http://dx.doi.org/10.1007/s11255-023-03520-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Urology - Original Paper
Higgins, Margaret M.
Wengryn, Derek
Koslov, David
Oliver, Janine
Flynn, Brian J.
Female urethroplasty with dorsal onlay buccal mucosal graft: a single institution experience
title Female urethroplasty with dorsal onlay buccal mucosal graft: a single institution experience
title_full Female urethroplasty with dorsal onlay buccal mucosal graft: a single institution experience
title_fullStr Female urethroplasty with dorsal onlay buccal mucosal graft: a single institution experience
title_full_unstemmed Female urethroplasty with dorsal onlay buccal mucosal graft: a single institution experience
title_short Female urethroplasty with dorsal onlay buccal mucosal graft: a single institution experience
title_sort female urethroplasty with dorsal onlay buccal mucosal graft: a single institution experience
topic Urology - Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105657/
https://www.ncbi.nlm.nih.gov/pubmed/36859624
http://dx.doi.org/10.1007/s11255-023-03520-5
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