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Calcineurin-dependent regulation of gap junction conductance and connexin phosphorylation in guinea pig left atrium

Atrial fibrillation (AF) occurs from disordered atrial action potential conduction and is associated with reduced gap junction electrical conductance (G(j)). The Ca(2+) and calmodulin-dependent phosphatase, calcineurin, reduces G(j) in ventricular myocardium via a protein phosphatase-1 (PP1)-depende...

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Detalles Bibliográficos
Autores principales: Jabr, R. I., Salvage, S. C., Hatch, F. S., Fry, C. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105670/
https://www.ncbi.nlm.nih.gov/pubmed/36917272
http://dx.doi.org/10.1007/s00424-023-02798-9

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