Efficacy of ketamine mouthwash in the management of oral and pharyngeal toxicity associated with head and neck chemoradiotherapy: protocol for a phase II, Simon’s two-stage trial

INTRODUCTION: Curative intent treatment of head and neck cancer (HNC) is frequently radiation therapy over 7 weeks with concurrent chemotherapy. This regimen is effective but carries a burden of toxicity leading to severe pain and treatment breaks portending inferior outcomes. Conventional palliatio...

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Detalles Bibliográficos
Autores principales: Koffler, Daniel, Eckstein, Jacob, Herman, Joseph, Martins-Welch, Diana, Seetharamu, Nagashree, Ghaly, Maged, Kohn, Nina, Potters, Louis, Frank, Douglas, Sullivan, Kevin, Parashar, Bhupesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10105995/
https://www.ncbi.nlm.nih.gov/pubmed/37041046
http://dx.doi.org/10.1136/bmjopen-2022-064809

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