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Lupus pathogenesis and autoimmunity are exacerbated by high fat diet-induced obesity in MRL/lpr mice

OBJECTIVE: SLE is an autoimmune disease characterised by persistent inflammation and autoantibody production. Genetic predisposition and environmental factors such as a high-fat diet (HFD) may contribute to lupus development. However, the immune cell profile and gender difference in response to HFD...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Meng, Juan, Shi, Xuhua, Quinet, Robert James, Davis, William, Zakem, Jerald, Keshavamurthy, Chandana, Patel, Ronak, Lobo, Gitanjali, Hellmers, Linh, Ray, Alicia Nicole, Rivers, Laura E, Ali, Hiba, Posas-Mendoza, Therese, Hille, Chad, You, Zongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106072/
https://www.ncbi.nlm.nih.gov/pubmed/37041033
http://dx.doi.org/10.1136/lupus-2023-000898