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Giant Cell Tumor of the Thoracic Spine in a Young Female Patient in a México City Spine Center: A Case Report

Patient: Female, 21-year-old Final Diagnosis: Giant cell tumor of the bone Symptoms: Back pain • diminished strength • hypoesthesia Clinical Procedure: — Specialty: Oncology • Orthopedics and Traumatology • Pathology OBJECTIVE: Unusual clinical course BACKGROUND: Giant cell tumors of the bone (GCTB)...

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Autores principales: Torres, Oscar Alejandro Chavira, Cojuc-Konigsberg, Gabriel, Becerril-Vargas, Eduardo, Haidenberg-David, Fabian, Olvera, Manuel Dufoo, Bernáldez, Guillermo Iván Ladewig, Oropeza, Edith, Colonna, Marzia Bezzerri, Santos, Saray Betsabe Torres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106095/
https://www.ncbi.nlm.nih.gov/pubmed/37036834
http://dx.doi.org/10.12659/AJCR.939086
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author Torres, Oscar Alejandro Chavira
Cojuc-Konigsberg, Gabriel
Becerril-Vargas, Eduardo
Haidenberg-David, Fabian
Olvera, Manuel Dufoo
Bernáldez, Guillermo Iván Ladewig
Oropeza, Edith
Colonna, Marzia Bezzerri
Santos, Saray Betsabe Torres
author_facet Torres, Oscar Alejandro Chavira
Cojuc-Konigsberg, Gabriel
Becerril-Vargas, Eduardo
Haidenberg-David, Fabian
Olvera, Manuel Dufoo
Bernáldez, Guillermo Iván Ladewig
Oropeza, Edith
Colonna, Marzia Bezzerri
Santos, Saray Betsabe Torres
author_sort Torres, Oscar Alejandro Chavira
collection PubMed
description Patient: Female, 21-year-old Final Diagnosis: Giant cell tumor of the bone Symptoms: Back pain • diminished strength • hypoesthesia Clinical Procedure: — Specialty: Oncology • Orthopedics and Traumatology • Pathology OBJECTIVE: Unusual clinical course BACKGROUND: Giant cell tumors of the bone (GCTB) are rare, locally aggressive benign neoplasms that primarily occur in the metaphyses of long bones. In less than 2% of cases, GCTBs arise in the spine, predominantly below the sacrum. We report the clinical manifestations, diagnostic approach, and successful surgical treatment of a patient with a GCTB of the thoracic spine. CASE REPORT: A 21-year-old female patient presented to the Emergency Department with back pain and upper motor neuron syndrome. A thorough clinical and imaging examination revealed a tumor and pathological fracture of the T7 vertebra. Histopathological analysis confirmed the diagnosis of a GCTB. The tumor was successfully excised surgically via a posterior thoracic approach, including bilateral decompressive laminectomy, lateral costotransversectomy, and posterior corpectomy, followed by transpedicular instrumentation of the T5–T6 and T8–T9 vertebrae, and anterior arthrodesis with an autologous graft. The patient also received adjuvant radiotherapy. One year later, the patient had no signs of recurrence or physical limitations. CONCLUSIONS: GCTBs located in the thoracic spine are uncommon and pose a significant challenge for healthcare professionals due to their non-specific clinical manifestations and the need for a multidisciplinary approach to their management. This case highlights the diagnostic and therapeutic implications of a GCTB of the thoracic spine and describes a successful surgical strategy resulting in complete recovery. The presented case adds to the limited published literature on GCTBs in this unusual location and further elaborates on their presentation and management.
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spelling pubmed-101060952023-04-17 Giant Cell Tumor of the Thoracic Spine in a Young Female Patient in a México City Spine Center: A Case Report Torres, Oscar Alejandro Chavira Cojuc-Konigsberg, Gabriel Becerril-Vargas, Eduardo Haidenberg-David, Fabian Olvera, Manuel Dufoo Bernáldez, Guillermo Iván Ladewig Oropeza, Edith Colonna, Marzia Bezzerri Santos, Saray Betsabe Torres Am J Case Rep Articles Patient: Female, 21-year-old Final Diagnosis: Giant cell tumor of the bone Symptoms: Back pain • diminished strength • hypoesthesia Clinical Procedure: — Specialty: Oncology • Orthopedics and Traumatology • Pathology OBJECTIVE: Unusual clinical course BACKGROUND: Giant cell tumors of the bone (GCTB) are rare, locally aggressive benign neoplasms that primarily occur in the metaphyses of long bones. In less than 2% of cases, GCTBs arise in the spine, predominantly below the sacrum. We report the clinical manifestations, diagnostic approach, and successful surgical treatment of a patient with a GCTB of the thoracic spine. CASE REPORT: A 21-year-old female patient presented to the Emergency Department with back pain and upper motor neuron syndrome. A thorough clinical and imaging examination revealed a tumor and pathological fracture of the T7 vertebra. Histopathological analysis confirmed the diagnosis of a GCTB. The tumor was successfully excised surgically via a posterior thoracic approach, including bilateral decompressive laminectomy, lateral costotransversectomy, and posterior corpectomy, followed by transpedicular instrumentation of the T5–T6 and T8–T9 vertebrae, and anterior arthrodesis with an autologous graft. The patient also received adjuvant radiotherapy. One year later, the patient had no signs of recurrence or physical limitations. CONCLUSIONS: GCTBs located in the thoracic spine are uncommon and pose a significant challenge for healthcare professionals due to their non-specific clinical manifestations and the need for a multidisciplinary approach to their management. This case highlights the diagnostic and therapeutic implications of a GCTB of the thoracic spine and describes a successful surgical strategy resulting in complete recovery. The presented case adds to the limited published literature on GCTBs in this unusual location and further elaborates on their presentation and management. International Scientific Literature, Inc. 2023-04-10 /pmc/articles/PMC10106095/ /pubmed/37036834 http://dx.doi.org/10.12659/AJCR.939086 Text en © Am J Case Rep, 2023 https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Articles
Torres, Oscar Alejandro Chavira
Cojuc-Konigsberg, Gabriel
Becerril-Vargas, Eduardo
Haidenberg-David, Fabian
Olvera, Manuel Dufoo
Bernáldez, Guillermo Iván Ladewig
Oropeza, Edith
Colonna, Marzia Bezzerri
Santos, Saray Betsabe Torres
Giant Cell Tumor of the Thoracic Spine in a Young Female Patient in a México City Spine Center: A Case Report
title Giant Cell Tumor of the Thoracic Spine in a Young Female Patient in a México City Spine Center: A Case Report
title_full Giant Cell Tumor of the Thoracic Spine in a Young Female Patient in a México City Spine Center: A Case Report
title_fullStr Giant Cell Tumor of the Thoracic Spine in a Young Female Patient in a México City Spine Center: A Case Report
title_full_unstemmed Giant Cell Tumor of the Thoracic Spine in a Young Female Patient in a México City Spine Center: A Case Report
title_short Giant Cell Tumor of the Thoracic Spine in a Young Female Patient in a México City Spine Center: A Case Report
title_sort giant cell tumor of the thoracic spine in a young female patient in a méxico city spine center: a case report
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106095/
https://www.ncbi.nlm.nih.gov/pubmed/37036834
http://dx.doi.org/10.12659/AJCR.939086
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