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Telomerase-mediated immortalization of human vaginal wall fibroblasts derived from patients with pelvic organ prolapse

BACKGROUND: Extracellular matrix (ECM) remodeling is the most important pathomechanism of pelvic organ prolapse (POP). Fibroblasts are the key to ECM regulation. The passaging capacity of human vaginal wall fibroblasts (hVWFs) is limited in vitro. Here, we aimed to immortalize hVWFs through the intr...

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Detalles Bibliográficos
Autores principales:	Guo, Tao, Xie, Ting, Lang, Jinghe, Sun, Zhijing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106167/ https://www.ncbi.nlm.nih.gov/pubmed/36914936 http://dx.doi.org/10.1097/CM9.0000000000002278

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