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Discovery of novel papain-like protease inhibitors for potential treatment of COVID-19

The recent emergence of different SARS-CoV-2 variants creates an urgent need to develop more effective therapeutic agents to prevent COVID-19 outbreaks. Among SARS-CoV-2 essential proteases is papain-like protease (SARS-CoV-2 PLpro), which plays multiple roles in regulating SARS-CoV-2 viral spread a...

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Detalles Bibliográficos
Autores principales: Hersi, Fatema, Sebastian, Anusha, Tarazi, Hamadeh, Srinivasulu, Vunnam, Mostafa, Ahmed, Allayeh, Abdou Kamal, Zeng, Cong, Hachim, Ibrahim Y., Liu, Shan-Lu, Abu-Yousef, Imad A., Majdalawieh, Amin F., Zaher, Dana M., Omar, Hany A., Al-Tel, Taleb H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106510/
https://www.ncbi.nlm.nih.gov/pubmed/37075625
http://dx.doi.org/10.1016/j.ejmech.2023.115380