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Sleep disruption and activation of cellular inflammation mediate heightened pain sensitivity: a randomized clinical trial
Sleep loss heightens pain sensitivity, but the pathways underlying this association are not known. Given that experimental sleep disruption induces increases in cellular inflammation as well as selective loss of slow wave, N3 sleep, this study examined whether these mechanisms contribute to pain sen...
Autores principales: | Irwin, Michael R., Olmstead, Richard, Bjurstrom, Martin F., Finan, Patrick H., Smith, Michael T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106531/ https://www.ncbi.nlm.nih.gov/pubmed/36314570 http://dx.doi.org/10.1097/j.pain.0000000000002811 |
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