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Case report: TMEM106B haplotype alters penetrance of GRN mutation in frontotemporal dementia family

Frontotemporal dementia (FTD) is the second-most common young-onset dementia. Variants in the TMEM106B gene have been proposed as modifiers of FTD disease risk, especially in progranulin (GRN) mutation carriers. A patient in their 50s presented to our clinic with behavioral variant FTD (bvFTD). Gene...

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Detalles Bibliográficos
Autores principales:	Perneel, Jolien, Manoochehri, Masood, Huey, Edward D., Rademakers, Rosa, Goldman, Jill
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106611/ https://www.ncbi.nlm.nih.gov/pubmed/37077569 http://dx.doi.org/10.3389/fneur.2023.1160248

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