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Myelin sheath injury and repairment after subarachnoid hemorrhage

Subarachnoid hemorrhage (SAH) can lead to damage to the myelin sheath in white matter. Through classification and analysis of relevant research results, the discussion in this paper provides a deeper understanding of the spatiotemporal change characteristics, pathophysiological mechanisms and treatm...

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Autores principales: Chen, Mao, Guo, Peiwen, Ru, Xufang, Chen, Yujie, Zuo, Shilun, Feng, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106687/
https://www.ncbi.nlm.nih.gov/pubmed/37077816
http://dx.doi.org/10.3389/fphar.2023.1145605
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author Chen, Mao
Guo, Peiwen
Ru, Xufang
Chen, Yujie
Zuo, Shilun
Feng, Hua
author_facet Chen, Mao
Guo, Peiwen
Ru, Xufang
Chen, Yujie
Zuo, Shilun
Feng, Hua
author_sort Chen, Mao
collection PubMed
description Subarachnoid hemorrhage (SAH) can lead to damage to the myelin sheath in white matter. Through classification and analysis of relevant research results, the discussion in this paper provides a deeper understanding of the spatiotemporal change characteristics, pathophysiological mechanisms and treatment strategies of myelin sheath injury after SAH. The research progress for this condition was also systematically reviewed and compared related to myelin sheath in other fields. Serious deficiencies were identified in the research on myelin sheath injury and treatment after SAH. It is necessary to focus on the overall situation and actively explore different treatment methods based on the spatiotemporal changes in the characteristics of the myelin sheath, as well as the initiation, intersection and common action point of the pathophysiological mechanism, to finally achieve accurate treatment. We hope that this article can help researchers in this field to further clarify the challenges and opportunities in the current research on myelin sheath injury and treatment after SAH.
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spelling pubmed-101066872023-04-18 Myelin sheath injury and repairment after subarachnoid hemorrhage Chen, Mao Guo, Peiwen Ru, Xufang Chen, Yujie Zuo, Shilun Feng, Hua Front Pharmacol Pharmacology Subarachnoid hemorrhage (SAH) can lead to damage to the myelin sheath in white matter. Through classification and analysis of relevant research results, the discussion in this paper provides a deeper understanding of the spatiotemporal change characteristics, pathophysiological mechanisms and treatment strategies of myelin sheath injury after SAH. The research progress for this condition was also systematically reviewed and compared related to myelin sheath in other fields. Serious deficiencies were identified in the research on myelin sheath injury and treatment after SAH. It is necessary to focus on the overall situation and actively explore different treatment methods based on the spatiotemporal changes in the characteristics of the myelin sheath, as well as the initiation, intersection and common action point of the pathophysiological mechanism, to finally achieve accurate treatment. We hope that this article can help researchers in this field to further clarify the challenges and opportunities in the current research on myelin sheath injury and treatment after SAH. Frontiers Media S.A. 2023-04-03 /pmc/articles/PMC10106687/ /pubmed/37077816 http://dx.doi.org/10.3389/fphar.2023.1145605 Text en Copyright © 2023 Chen, Guo, Ru, Chen, Zuo and Feng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Chen, Mao
Guo, Peiwen
Ru, Xufang
Chen, Yujie
Zuo, Shilun
Feng, Hua
Myelin sheath injury and repairment after subarachnoid hemorrhage
title Myelin sheath injury and repairment after subarachnoid hemorrhage
title_full Myelin sheath injury and repairment after subarachnoid hemorrhage
title_fullStr Myelin sheath injury and repairment after subarachnoid hemorrhage
title_full_unstemmed Myelin sheath injury and repairment after subarachnoid hemorrhage
title_short Myelin sheath injury and repairment after subarachnoid hemorrhage
title_sort myelin sheath injury and repairment after subarachnoid hemorrhage
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106687/
https://www.ncbi.nlm.nih.gov/pubmed/37077816
http://dx.doi.org/10.3389/fphar.2023.1145605
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