Telomere dysfunction in some pediatric congenital and growth-related diseases

Telomere wear and dysfunction may lead to aging-related diseases. Moreover, increasing evidence show that the occurrence, development, and prognosis of some pediatric diseases are also related to telomere dysfunction. In this review, we systematically analyzed the relationship between telomere biolo...

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Detalles Bibliográficos
Autores principales: Zheng, Bo, Fu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106694/
https://www.ncbi.nlm.nih.gov/pubmed/37077333
http://dx.doi.org/10.3389/fped.2023.1133102
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author Zheng, Bo
Fu, Jianhua
author_facet Zheng, Bo
Fu, Jianhua
author_sort Zheng, Bo
collection PubMed
description Telomere wear and dysfunction may lead to aging-related diseases. Moreover, increasing evidence show that the occurrence, development, and prognosis of some pediatric diseases are also related to telomere dysfunction. In this review, we systematically analyzed the relationship between telomere biology and some pediatric congenital and growth-related diseases and proposed new theoretical basis and therapeutic targets for the treatment of these diseases.
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spelling pubmed-101066942023-04-18 Telomere dysfunction in some pediatric congenital and growth-related diseases Zheng, Bo Fu, Jianhua Front Pediatr Pediatrics Telomere wear and dysfunction may lead to aging-related diseases. Moreover, increasing evidence show that the occurrence, development, and prognosis of some pediatric diseases are also related to telomere dysfunction. In this review, we systematically analyzed the relationship between telomere biology and some pediatric congenital and growth-related diseases and proposed new theoretical basis and therapeutic targets for the treatment of these diseases. Frontiers Media S.A. 2023-04-03 /pmc/articles/PMC10106694/ /pubmed/37077333 http://dx.doi.org/10.3389/fped.2023.1133102 Text en © 2023 Zheng and Fu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Zheng, Bo
Fu, Jianhua
Telomere dysfunction in some pediatric congenital and growth-related diseases
title Telomere dysfunction in some pediatric congenital and growth-related diseases
title_full Telomere dysfunction in some pediatric congenital and growth-related diseases
title_fullStr Telomere dysfunction in some pediatric congenital and growth-related diseases
title_full_unstemmed Telomere dysfunction in some pediatric congenital and growth-related diseases
title_short Telomere dysfunction in some pediatric congenital and growth-related diseases
title_sort telomere dysfunction in some pediatric congenital and growth-related diseases
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106694/
https://www.ncbi.nlm.nih.gov/pubmed/37077333
http://dx.doi.org/10.3389/fped.2023.1133102
work_keys_str_mv AT zhengbo telomeredysfunctioninsomepediatriccongenitalandgrowthrelateddiseases
AT fujianhua telomeredysfunctioninsomepediatriccongenitalandgrowthrelateddiseases

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