Rhodopsin-associated retinal dystrophy: Disease mechanisms and therapeutic strategies

Rhodopsin is a light-sensitive G protein-coupled receptor that initiates the phototransduction cascade in rod photoreceptors. Mutations in the rhodopsin-encoding gene RHO are the leading cause of autosomal dominant retinitis pigmentosa (ADRP). To date, more than 200 mutations have been identified in...

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Detalles Bibliográficos
Autores principales: Zhen, Fangyuan, Zou, Tongdan, Wang, Ting, Zhou, Yongwei, Dong, Shuqian, Zhang, Houbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106759/
https://www.ncbi.nlm.nih.gov/pubmed/37077319
http://dx.doi.org/10.3389/fnins.2023.1132179

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