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Clinical impacts of the concomitant use of L-asparaginase and total parenteral nutrition containing L-aspartic acid in patients with acute lymphoblastic leukemia

INTRODUCTION: L-asparaginase (ASNase) depletes L-asparagine and causes the death of leukemic cells, making it a mainstay for the treatment of acute lymphoblastic leukemia (ALL). However, ASNase's activity can be inhibited by L-aspartic acid (Asp), which competes for the same substrate and reduc...

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Detalles Bibliográficos
Autores principales:	Ko, Minoh, Kim, Myeong Gyu, Yoon, Sung-Soo, Kim, In-Wha, Suh, Sung Yun, Cho, Yoon-Sook, Oh, Jung Mi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Nutrition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106764/ https://www.ncbi.nlm.nih.gov/pubmed/37077904 http://dx.doi.org/10.3389/fnut.2023.1122010

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