Cargando…

Time trends and heterogeneity in the disease burden of visual impairment due to cataract, 1990–2019: A global analysis

OBJECTIVES: This study aimed to estimate the disease burden of cataract and evaluate the contributions of risk factors to cataract-associated disability-adjusted life years (DALYs). MATERIALS AND METHODS: Prevalence and DALYs of visual impairment due to cataract were extracted from the Global Burden...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Xiaotong, Zou, Minjie, Liu, Zhenzhen, Sun, Yi, Young, Charlotte Aimee, Zheng, Danying, Jin, Guangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106776/
https://www.ncbi.nlm.nih.gov/pubmed/37077196
http://dx.doi.org/10.3389/fpubh.2023.1140533
_version_ 1785026479654961152
author Han, Xiaotong
Zou, Minjie
Liu, Zhenzhen
Sun, Yi
Young, Charlotte Aimee
Zheng, Danying
Jin, Guangming
author_facet Han, Xiaotong
Zou, Minjie
Liu, Zhenzhen
Sun, Yi
Young, Charlotte Aimee
Zheng, Danying
Jin, Guangming
author_sort Han, Xiaotong
collection PubMed
description OBJECTIVES: This study aimed to estimate the disease burden of cataract and evaluate the contributions of risk factors to cataract-associated disability-adjusted life years (DALYs). MATERIALS AND METHODS: Prevalence and DALYs of visual impairment due to cataract were extracted from the Global Burden of Disease (GBD) study 2019 to explore time trends and annual changes. Regional and country-level socioeconomic indexes were obtained from open databases. The time trend of prevalence and DALYs was demonstrated. Stepwise multiple linear regression was used to evaluate associations between the age-standardized rate of DALYs of cataract and potential predictors. RESULTS: Global Prevalence rate of visual impairment due to cataract rose by 58.45% to 1,253.9 per 100,000 population (95% CI: 1,103.3 to 1,417.7 per 100,000 population) in 2019 and the DALYs rate rose by 32.18% from 65.3 per 100,000 population (95% CI: 46.4 to 88.2 per 100,000 population) in 1990 to 86.3 per 100,000 population (95% CI: 61.5 to 116.4 per 100,000 population) in 2019. Stepwise multiple linear regression model showed that higher refractive error prevalence (β = 0.036, 95% CI: 0.022, 0.050, P < 0.001), lower number of physicians per 10,000 population (β = −0.959, 95% CI: −1.685, −0.233, P = 0.010), and lower level of HDI (β = −134.93, 95% CI: −209.84, −60.02, P = 0.001) were associated with a higher disease burden of cataract. CONCLUSION: Substantial increases in the prevalence of visual impairment and DALYs of cataract were observed from 1990 to 2019. Successful global initiatives targeting improving cataract surgical rate and quality, especially in regions with lower socioeconomic status, is a prerequisite to combating this growing burden of cataract in the aging society.
format Online
Article
Text
id pubmed-10106776
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-101067762023-04-18 Time trends and heterogeneity in the disease burden of visual impairment due to cataract, 1990–2019: A global analysis Han, Xiaotong Zou, Minjie Liu, Zhenzhen Sun, Yi Young, Charlotte Aimee Zheng, Danying Jin, Guangming Front Public Health Public Health OBJECTIVES: This study aimed to estimate the disease burden of cataract and evaluate the contributions of risk factors to cataract-associated disability-adjusted life years (DALYs). MATERIALS AND METHODS: Prevalence and DALYs of visual impairment due to cataract were extracted from the Global Burden of Disease (GBD) study 2019 to explore time trends and annual changes. Regional and country-level socioeconomic indexes were obtained from open databases. The time trend of prevalence and DALYs was demonstrated. Stepwise multiple linear regression was used to evaluate associations between the age-standardized rate of DALYs of cataract and potential predictors. RESULTS: Global Prevalence rate of visual impairment due to cataract rose by 58.45% to 1,253.9 per 100,000 population (95% CI: 1,103.3 to 1,417.7 per 100,000 population) in 2019 and the DALYs rate rose by 32.18% from 65.3 per 100,000 population (95% CI: 46.4 to 88.2 per 100,000 population) in 1990 to 86.3 per 100,000 population (95% CI: 61.5 to 116.4 per 100,000 population) in 2019. Stepwise multiple linear regression model showed that higher refractive error prevalence (β = 0.036, 95% CI: 0.022, 0.050, P < 0.001), lower number of physicians per 10,000 population (β = −0.959, 95% CI: −1.685, −0.233, P = 0.010), and lower level of HDI (β = −134.93, 95% CI: −209.84, −60.02, P = 0.001) were associated with a higher disease burden of cataract. CONCLUSION: Substantial increases in the prevalence of visual impairment and DALYs of cataract were observed from 1990 to 2019. Successful global initiatives targeting improving cataract surgical rate and quality, especially in regions with lower socioeconomic status, is a prerequisite to combating this growing burden of cataract in the aging society. Frontiers Media S.A. 2023-04-03 /pmc/articles/PMC10106776/ /pubmed/37077196 http://dx.doi.org/10.3389/fpubh.2023.1140533 Text en Copyright © 2023 Han, Zou, Liu, Sun, Young, Zheng and Jin. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Han, Xiaotong
Zou, Minjie
Liu, Zhenzhen
Sun, Yi
Young, Charlotte Aimee
Zheng, Danying
Jin, Guangming
Time trends and heterogeneity in the disease burden of visual impairment due to cataract, 1990–2019: A global analysis
title Time trends and heterogeneity in the disease burden of visual impairment due to cataract, 1990–2019: A global analysis
title_full Time trends and heterogeneity in the disease burden of visual impairment due to cataract, 1990–2019: A global analysis
title_fullStr Time trends and heterogeneity in the disease burden of visual impairment due to cataract, 1990–2019: A global analysis
title_full_unstemmed Time trends and heterogeneity in the disease burden of visual impairment due to cataract, 1990–2019: A global analysis
title_short Time trends and heterogeneity in the disease burden of visual impairment due to cataract, 1990–2019: A global analysis
title_sort time trends and heterogeneity in the disease burden of visual impairment due to cataract, 1990–2019: a global analysis
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106776/
https://www.ncbi.nlm.nih.gov/pubmed/37077196
http://dx.doi.org/10.3389/fpubh.2023.1140533
work_keys_str_mv AT hanxiaotong timetrendsandheterogeneityinthediseaseburdenofvisualimpairmentduetocataract19902019aglobalanalysis
AT zouminjie timetrendsandheterogeneityinthediseaseburdenofvisualimpairmentduetocataract19902019aglobalanalysis
AT liuzhenzhen timetrendsandheterogeneityinthediseaseburdenofvisualimpairmentduetocataract19902019aglobalanalysis
AT sunyi timetrendsandheterogeneityinthediseaseburdenofvisualimpairmentduetocataract19902019aglobalanalysis
AT youngcharlotteaimee timetrendsandheterogeneityinthediseaseburdenofvisualimpairmentduetocataract19902019aglobalanalysis
AT zhengdanying timetrendsandheterogeneityinthediseaseburdenofvisualimpairmentduetocataract19902019aglobalanalysis
AT jinguangming timetrendsandheterogeneityinthediseaseburdenofvisualimpairmentduetocataract19902019aglobalanalysis