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Distinct subpopulations of DN1 thymocytes exhibit preferential γδ T lineage potential

The αβ and γδ T cell lineages both differentiate in the thymus from common uncommitted progenitors. The earliest stage of T cell development is known as CD4(-)CD8(-) double negative 1 (DN1), which has previously been shown to be a heterogenous mixture of cells. Of these, only the CD117(+) fraction h...

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Detalles Bibliográficos
Autores principales: Oh, Seungyoul, Liu, Xin, Tomei, Sara, Luo, Mengxiao, Skinner, Jarrod P., Berzins, Stuart P., Naik, Shalin H., Gray, Daniel H. D., Chong, Mark M. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106834/
https://www.ncbi.nlm.nih.gov/pubmed/37077921
http://dx.doi.org/10.3389/fimmu.2023.1106652