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Distinct subpopulations of DN1 thymocytes exhibit preferential γδ T lineage potential
The αβ and γδ T cell lineages both differentiate in the thymus from common uncommitted progenitors. The earliest stage of T cell development is known as CD4(-)CD8(-) double negative 1 (DN1), which has previously been shown to be a heterogenous mixture of cells. Of these, only the CD117(+) fraction h...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106834/ https://www.ncbi.nlm.nih.gov/pubmed/37077921 http://dx.doi.org/10.3389/fimmu.2023.1106652 |