Detection of pre-existing neutralizing antibodies against Ad26 in HIV-1-infected individuals not responding to the Ad26.COV2.S vaccine

PURPOSE: The Ad26.COV2.S vaccine is a replication-incompetent human adenovirus type 26 vector encoding the SARS-CoV-2 spike protein. In a phase 1-2a trial, a single dose of Ad26.COV2.S induced SARS-CoV-2 spike-specific antibodies in ≥ 96% of healthy adults. To investigate vaccine immunogenicity in H...

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Detalles Bibliográficos
Autores principales: Schmidt, Katja G., Harrer, Ellen G., Schönau, Verena, Simon, David, Kleyer, Arnd, Steininger, Philipp, Korn, Klaus, Schett, Georg, Knobloch, Carina S., Nganou-Makamdop, Krystelle, Harrer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106868/
https://www.ncbi.nlm.nih.gov/pubmed/37067754
http://dx.doi.org/10.1007/s15010-023-02035-6

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