Intranasal booster using an Omicron vaccine confers broad mucosal and systemic immunity against SARS-CoV-2 variants

The highly contagious SARS-CoV-2 Omicron subvariants severely attenuated the effectiveness of currently licensed SARS-CoV-2 vaccines based on ancestral strains administered via intramuscular injection. In this study, we generated a recombinant, replication-incompetent human adenovirus type 5, Ad5-S-...

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Detalles Bibliográficos
Autores principales: Wang, Qian, Yang, Chenchen, Yin, Li, Sun, Jing, Wang, Wei, Li, Hengchun, Zhang, Zhengyuan, Chen, Si, Liu, Bo, Liu, Zijian, Shi, Linjing, Liu, Xiaolin, Guan, Suhua, Wang, Chunhua, Qu, Linbing, Feng, Ying, Niu, Xuefeng, Feng, Liqiang, Zhao, Jincun, Li, Pingchao, Chen, Ling, Zhong, Nanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106878/
https://www.ncbi.nlm.nih.gov/pubmed/37069171
http://dx.doi.org/10.1038/s41392-023-01423-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106878/
https://www.ncbi.nlm.nih.gov/pubmed/37069171
http://dx.doi.org/10.1038/s41392-023-01423-6

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