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Efficacy of PBTZ169 and pretomanid against Mycobacterium avium, Mycobacterium abscessus, Mycobacterium chelonae, and Mycobacterium fortuitum in BALB/c mice models

OBJECTIVES: We aimed to evaluate the activity of PBTZ169 and pretomanid against non-tuberculous mycobacteriosis (NTM) in vitro and in vivo. METHODS: The minimum inhibitory concentrations (MICs) of 11 antibiotics, against slow-growing mycobacteria (SGMs) and rapid-growing mycobacteria (RGMs) were tes...

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Detalles Bibliográficos
Autores principales: Zheng, Luyao, Qi, Xueting, Zhang, Weiyan, Wang, Hong, Fu, Lei, Wang, Bin, Chen, Xi, Chen, Xiaoyou, Lu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10106926/
https://www.ncbi.nlm.nih.gov/pubmed/37077530
http://dx.doi.org/10.3389/fcimb.2023.1115530